News Feature
Published: 28 April 2025
Melanie Senior 1
Nature Biotechnology
(2025)Cite this article
Developers are recombining or sharpening established drugs, molecules and mechanisms to create a new generation of neurology therapies.
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
24,99 € / 30 days
cancel any time
Subscribe to this journal
Receive 12 print issues and online access
209,00 € per year
only 17,42 € per issue
Buy this article
Purchase on SpringerLink
Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Additional access options:
Log in
Learn about institutional subscriptions
Read our FAQs
Contact customer support
Fig. 1: Since 2020, only cancer surpasses neurology in overall M&A value.
References Harrison, C. Nat. Biotechnol. 43, 287–289 (2025).
Article
CAS
PubMed
Google Scholar
McDermott, L. A. et al. Neuron https://doi.org/10.1016/j.neuron.2019.01.047 (2019).
Article
PubMed
PubMed Central
Google Scholar
Knowland, D. et al. J. Clin. Invest. https://doi.org/10.1172/JCI140311 (2020).
Article
PubMed
PubMed Central
Google Scholar
Wieskopf, J. S. et al. Sci. Transl. Med. https://doi.org/10.1126/scitranslmed.3009986 (2015).
Article
PubMed
PubMed Central
Google Scholar
Conaghan, P. et al. In ACR Convergence 2024 https://acrabstracts.org/abstract/levi-04-a-novel-neurotrophin-3-inhibitor-substantially-improves-pain-and-function-without-deleterious-effects-on-joint-structure-in-people-with-knee-osteoarthritis-a-randomized-controlled-phase-ii/ (2024).
Zhang, M. et al. Signal Transduct. Target. Ther. https://doi.org/10.1038/s41392-023-01464-x (2023).
Article
PubMed
PubMed Central
Google Scholar
Khairatkar-Joshi, N. & Szallasi, A. Trends Mol. Med. https://doi.org/10.1016/j.molmed.2008.11.004 (2009).
Article
PubMed
Google Scholar
Finol-Urdaneta, R. K. et al. Proc. Natl Acad. Sci. USA https://doi.org/10.1073/pnas.2110932119 (2022).
Article
PubMed
PubMed Central
Google Scholar
Cao, B. et al. Signal Transduct. Target. Ther. https://doi.org/10.1038/s41392-024-01845-w (2024).
Gahr, M., Kratzer, W., Fuchs, M. & Connemann, B. J. et al. Curr. Drug Metab. https://doi.org/10.2174/1389200215666140926155041 (2014).
Article
PubMed
Google Scholar
Bremova-Ertl, T. et al. N. Engl. J. Med. https://doi.org/10.1056/NEJMoa2310151 (2024).
Article
PubMed
Google Scholar
Churchill, G. C., Strupp, M., Galione, A. & Platt, F. M. et al. PLoS One https://doi.org/10.1371/journal.pone.0229585 (2020).
Article
PubMed
PubMed Central
Google Scholar
Oertel, W. H. et al. Nat. Commun. https://doi.org/10.1038/s41467-024-51502-7 (2024).
Article
PubMed
PubMed Central
Google Scholar
Al-zharani, M., Hasnain, M. S., Al-Eissa, M. S. & Alqahtani, R. A. et al. J. King Saud Univ. Sci. https://doi.org/10.1016/j.jksus.2024.103513 (2024).
Article
Google Scholar
Razavi, R., Khajouei, G., Divsalar, F., Dawi, E. & Amiri, M. et al. Rev. Neurosci. https://doi.org/10.1515/revneuro-2024-0086 (2024).
Article
Google Scholar
Download references
Author information Authors and Affiliations London, UK
Melanie Senior
Rights and permissions About this article
Cite this article Senior, M. Precision neuroscience.
Nat Biotechnol (2025). https://doi.org/10.1038/s41587-025-02673-1
Download citation
Published: 28 April 2025
DOI : https://doi.org/10.1038/s41587-025-02673-1
Leave a Reply