A minimal complex of KHNYN and zinc-finger antiviral protein binds and degrades single-stranded RNA

Proceedings of the National Academy of Sciences, Volume 121, Issue 52, December 2024.
SignificanceIn cells, ZAP (zinc-finger antiviral protein) and KHNYN (KH-like and NYN domain containing protein) act together with partners to recognize and deplete viral RNA containing CpG dinucleotide clusters. Using purified recombinant proteins and …
Read whole article here