Artificial dynamic structure ensemble-guided rational design of a universal RNA aptamer–based sensing tag

Proceedings of the National Academy of Sciences, Volume 121, Issue 52, December 2024.
SignificanceTo open different horizons for universal FRApt-based sensor generation, we developed the concept of ensemble modularity with dynamic tuning and created an artificial dynamic RNA ensemble “SSPepper.” SSPepper served as a dynamic adjustability …
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